Signal peptide independent protein secretion mechanism of gram-negative bacteria.
نویسندگان
چکیده
منابع مشابه
Protein Secretion Systems in Gram-Negative Bacteria
P rotein export systems are present in all living organisms, including gram-negative bacteria and the eukaryotic organelles that derived from them (Table 1). In contrast to other organisms, however, gram-negative bacteria contain numerous, apparently independent systems for exporting proteins, including at least eight types that mediate export across or insertion into the inner cytoplasmic memb...
متن کاملDeterminants of extracellular protein secretion in gram-negative bacteria.
Protein localization has been the subject of extensive research using models ranging from bacteria to mammalian cells. The central question which prokaryoticand eukaryotic-cell biologists have attempted to answer is how proteins synthesized in the cytoplasmic compartment traverse the hydrophobic membrane barrier or become integrated into it. This work has led to the identification of targeting ...
متن کاملMechanisms of Antimicrobial Peptide Resistance in Gram-Negative Bacteria
Cationic antimicrobial peptides (CAMPs) are important innate immune defenses that inhibit colonization by pathogens and contribute to clearance of infections. Gram-negative bacterial pathogens are a major target, yet many of them have evolved mechanisms to resist these antimicrobials. These resistance mechanisms can be critical contributors to bacterial virulence and are often crucial for survi...
متن کاملPrediction of lipoprotein signal peptides in Gram-negative bacteria.
A method to predict lipoprotein signal peptides in Gram-negative Eubacteria, LipoP, has been developed. The hidden Markov model (HMM) was able to distinguish between lipoproteins (SPaseII-cleaved proteins), SPaseI-cleaved proteins, cytoplasmic proteins, and transmembrane proteins. This predictor was able to predict 96.8% of the lipoproteins correctly with only 0.3% false positives in a set of S...
متن کاملMechanism of antibiotic efflux in Gram-negative bacteria.
Active efflux of antibiotics mediated by multidrug transporters is a mechanistic basis of multidrug resistance in bacteria. The most versatile multidrug transporters are those found in Gram-negative bacteria. They have a high level of constitutive expression and provide an immediate response to structurally diverse antimicrobial agents including clinically important antibiotics. The versatility...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Kagaku To Seibutsu
سال: 1997
ISSN: 0453-073X,1883-6852
DOI: 10.1271/kagakutoseibutsu1962.35.132